The Mouse CD16/32 Monoclonal Antibody (AF647 conjugated 2.4G2, AGEL0596) available at Assaygenie is a powerful tool for research involving cell surface markers in immunology studies. This monoclonal antibody specifically targets CD16/32, which are key receptors involved in immune cell activation and phagocytosis.Derived from hybridoma cells, this antibody is conjugated with AF647 for fluorescent detection, allowing for precise visualization and analysis of CD16/32 expression in various cell types. This product has been rigorously validated for use in flow cytometry applications, providing researchers with reliable and accurate results.
CD16/32, also known as Fc gamma receptor III (CD16) and Fc gamma receptor II (CD32), play essential roles in mediating antibody-dependent cellular cytotoxicity and phagocytosis. Understanding the expression and function of these receptors is crucial for the study of immune responses, autoimmune diseases, and infectious conditions.By utilizing the Mouse CD16/32 Monoclonal Antibody (AF647 conjugated 2.4G2, AGEL0596), researchers can delve deeper into the intricate mechanisms of immune cell interactions and potentially uncover novel therapeutic targets for immune-related disorders.
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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