PE Anti-Mouse CD150 Antibody [TC15-12F12.2] (AGEL1881)

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SKU:
AGEL1881
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse CD150 Antibody [TC15-12F12.2]

The Mouse CD150 Monoclonal Antibody (PE Conjugated, TC15-12F12.2, AGEL1881) is a cutting-edge tool for researchers studying CD150, a key cell surface marker involved in immune regulation and hematopoiesis. This antibody, produced through innovative monoclonal antibody technology, is specifically designed for use in flow cytometry and fluorescence microscopy applications, enabling precise detection and analysis of CD150 expression in mouse samples.CD150, also known as Signaling Lymphocytic Activation Molecule (SLAM) receptor, plays a crucial role in immune cell activation and proliferation, making it a pivotal target for investigation in immunology, stem cell research, and vaccine development.

By targeting CD150, researchers can better understand its role in immune responses, hematopoietic cell differentiation, and the development of immune-based therapies for diseases such as leukemia and autoimmune disorders.With its high specificity and sensitivity, the Mouse CD150 Monoclonal Antibody (PE Conjugated) is a valuable tool for scientists exploring the intricate mechanisms of immune function and hematopoiesis. Its reliable performance and compatibility with various experimental techniques make it an indispensable asset for advancing research in immunology and related fields.

Product Title:PE Anti-Mouse CD150 Antibody [TC15-12F12.2]
SKU:AGEL1881
Size:50 Tests, 100 Tests, 200 Tests
Clone No:TC15-12F12.2
Synonyms:Slam;Slamf1;CD 150;Signaling lymphocytic activation molecule;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, λ
Isotype Control:PE Rat IgG2a, λ Isotype Control[B39-4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QUM4
Gene ID:27218
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

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