The Mouse CD14 Monoclonal Antibody (PE/Cyanine5 Conjugated) (SA14-2) is a valuable tool for researchers studying CD14, a key cell surface marker involved in the immune response. This antibody, designed for use in flow cytometry applications, reacts specifically with mouse samples and is conjugated to PE/Cyanine5 for easy detection and analysis.CD14 is a crucial component of the innate immune system, acting as a co-receptor for various Toll-like receptors and playing a role in the recognition of bacterial lipopolysaccharides. Its expression on monocytes and macrophages makes it an important target for studying immune responses to infection, inflammation, and autoimmune diseases.
By using the Mouse CD14 Monoclonal Antibody (PE/Cyanine5 Conjugated), researchers can accurately identify and analyze CD14 expression in different cell populations, shedding light on the mechanisms underlying immune regulation and inflammatory processes. This antibody is a valuable tool for studies in immunology, infectious diseases, and inflammation, providing insights that may lead to the development of novel therapies targeting CD14 and related pathways.
Product Title:
PE/Cyanine5 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL1875
Size:
25µg, 100µg
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.
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