PE/Cyanine5.5 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1877)

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SKU:
AGEL1877
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody (PE/Cyanine5.5 Conjugated), clone SA14-2 (AGEL1877), offered by Assay Genie, is a powerful tool for researchers studying immune responses and inflammation in mouse models.This monoclonal antibody is specifically designed to target CD14, a cell surface receptor found on monocytes, macrophages, and dendritic cells. CD14 plays a crucial role in the recognition of bacterial lipopolysaccharides (LPS) and initiation of inflammatory responses. By binding to CD14, this antibody enables the detection and analysis of CD14-expressing cells, allowing for a better understanding of immune activation and regulation.With its PE/Cyanine5.

5 conjugation, this antibody is suited for flow cytometry applications, providing researchers with a reliable method to analyze immune cell populations in complex samples. Its specificity for mouse CD14 makes it a valuable tool for studies focusing on innate immune responses, infectious diseases, and inflammation in preclinical models.By utilizing the Mouse CD14 Monoclonal Antibody (PE/Cyanine5.5 Conjugated), researchers can gain insights into the dynamics of immune cell activation and inflammation, paving the way for the development of novel therapies targeting immune-related disorders and inflammatory conditions in mouse models.

Product Title:PE/Cyanine5.5 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1877
Size:25µg, 100µg
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

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