The SA14-2 (AGEL1864) Mouse CD14 Monoclonal Antibody PE Conjugated is a valuable tool for researchers investigating immune responses and inflammatory processes. This antibody, designed for use with mouse samples, targets the CD14 protein, a key component of the innate immune system involved in the detection of bacterial lipopolysaccharides. The PE-conjugated SA14-2 antibody allows for easy detection and analysis of CD14 in various cell types, making it an ideal choice for studies related to immunology, infection, and inflammation. By binding specifically to CD14, this monoclonal antibody enables precise identification and characterization of immune cells expressing this protein, providing valuable insights into the mechanisms underlying immune responses.
With its high reactivity and specificity for mouse CD14, the SA14-2 Monoclonal Antibody is a valuable tool for researchers studying immune system function, host-pathogen interactions, and inflammatory diseases. Whether used in flow cytometry, immunofluorescence, or other applications, this antibody provides reliable and accurate detection of CD14, facilitating in-depth investigations into the role of this protein in immune regulation and disease pathogenesis.
Product Title:
PE Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL1864
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.