FITC Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1872)

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SKU:
AGEL1872
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody (FITC-conjugated, SA14-2) is a valuable tool for researchers studying CD14, a key cell surface antigen involved in immune responses. This antibody, derived from a monoclonal source, has been specifically conjugated with FITC for easy visualization and detection in flow cytometry and fluorescence microscopy applications.CD14 is known for its role in innate immunity, particularly in the recognition of bacterial lipopolysaccharide and other microbial components. By targeting CD14, researchers can explore the activation and regulation of immune responses in various cell types, shedding light on pathways involved in inflammatory processes and host defense mechanisms.

The FITC-conjugated SA14-2 antibody offers high specificity and sensitivity for detecting CD14 expression in mouse samples, providing reliable results for immunological studies. Its versatility makes it suitable for a range of experimental settings, from characterizing immune cell populations to investigating inflammatory conditions and infectious diseases in mouse models.By utilizing the Mouse CD14 Monoclonal Antibody (FITC-conjugated, SA14-2), researchers can delve deeper into the intricate mechanisms governing immune responses and potentially uncover novel insights that contribute to the development of therapeutic interventions targeting immune-related disorders.

Product Title:FITC Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1872
Size:25µg, 100µg
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

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