The Mouse CD14 Monoclonal Antibody (FITC Conjugated, SA14-2) is a powerful tool for researchers studying the CD14 protein, a key component of the innate immune system. This antibody, specifically designed for use in flow cytometry applications, is ideal for detecting and analyzing CD14 in mouse samples. CD14 is a crucial receptor involved in the recognition of bacterial lipopolysaccharides, triggering inflammatory responses and playing a pivotal role in the host defense against infections. The FITC-conjugated SA14-2 antibody enables precise visualization and quantification of CD14 expression on various immune cell populations, providing valuable insights into immune responses and inflammation.
By targeting CD14 with this monoclonal antibody, researchers can investigate the role of this receptor in infections, inflammatory diseases, and immune system regulation. With its high specificity and sensitivity, the Mouse CD14 Monoclonal Antibody (FITC Conjugated, SA14-2) is a reliable tool for advancing research in immunology, infectious diseases, and related fields.
Product Title:
FITC Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL1863
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.