The Mouse CD14 Monoclonal Antibody (AF647 Conjugated) SA14-2 (AGel1880) is a powerful tool for researchers interested in studying CD14, a key cell surface marker involved in the recognition of bacterial lipopolysaccharide and the initiation of inflammatory responses. This monoclonal antibody, conjugated with AF647 for fluorescent detection, is specifically designed for flow cytometry applications in mouse samples, providing high sensitivity and specificity.CD14 is a crucial component of the innate immune system, functioning as a co-receptor for toll-like receptors and promoting the activation of pro-inflammatory pathways. By targeting CD14 with this monoclonal antibody, researchers can accurately identify and quantify CD14-expressing cell populations, aiding in the understanding of immune responses in infection, inflammation, and immune-related diseases.
With its high specificity and fluorescence conjugation, the Mouse CD14 Monoclonal Antibody (AF647 Conjugated) SA14-2 (AGel1880) offers a reliable solution for immunophenotyping and functional studies in mouse models. Its application extends to a wide range of research areas, including immunology, microbiology, and inflammation, making it a valuable asset in the exploration of immune system dynamics and host-pathogen interactions.
Product Title:
GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL1880
Size:
25µg, 100µg
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.
![GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1880)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/608x608/products/122279/120459/AGEL1880__75845__94056.1732016513.jpg?c=1 "GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1880)")
![GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1880)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/1280x1280/products/122279/120459/AGEL1880__75845__94056.1732016513.jpg?c=1&imbypass=on "GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1880)")
![GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1871)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122270/120450/geniefluor-647-anti-mouse-cd14-antibody-sa14-2-agel1871__67746__64594.1732016509.jpg?c=1 "GenieFluor 647 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1871)")
![GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1870)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122269/120449/geniefluor-488-anti-mouse-cd14-antibody-sa14-2-agel1870__27574__06498.1732016508.jpg?c=1 "GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1870)")
![GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1879)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122278/120458/geniefluor-488-anti-mouse-cd14-antibody-sa14-2-agel1879__90796__73264.1732016513.jpg?c=1 "GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1879)")
![FITC Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1863)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122262/120442/AGEL1863__66981__24327.1732016505.jpg?c=1 "FITC Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1863)")
![FITC Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1872)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/122271/120451/AGEL1872__40223__04943.1732016509.jpg?c=1 "FITC Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1872)")