GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1870)

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SKU:
AGEL1870
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody (AF488 Conjugated) SA14-2 (AGEL1870) is a vital tool for researchers investigating the role of CD14 in immune responses and inflammatory processes. CD14 is a surface marker found on monocytes, macrophages, and other immune cells, playing a key role in the recognition of bacterial lipopolysaccharides and initiating inflammatory responses.This monoclonal antibody, conjugated with Alexa Fluor 488 for fluorescent detection, specifically targets and binds to CD14, allowing for precise visualization and analysis of CD14 expression in various cell types and tissues. Its use is validated for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, providing researchers with versatile options for studying CD14 function in different experimental settings.

Understanding the mechanisms by which CD14 contributes to immune responses is crucial for unraveling the complexities of inflammatory diseases, sepsis, and host defense against infections. By using the Mouse CD14 Monoclonal Antibody (AF488 Conjugated) SA14-2 (AGEL1870), researchers can delve deeper into the intricate workings of the immune system and potentially identify new therapeutic targets for treating a range of inflammatory conditions.

Product Title:GenieFluor 488 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1870
Size:50 Tests, 100 Tests, 200 Tests
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.

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