The Mouse CD127 IL-7RA Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) - A7R34 (AGEL0743) is a specialized tool for researchers studying the CD127 protein, also known as IL-7 receptor alpha, on mouse cells. This monoclonal antibody, labeled with PerCP-Cyanine5.5, offers high specificity and sensitivity in various experimental applications.CD127 is a crucial component of the IL-7 receptor complex, essential for lymphocyte development and homeostasis. By targeting CD127 with this monoclonal antibody, researchers can accurately detect and quantify the expression of this receptor on immune cells and investigate its role in immune responses and lymphocyte function.
Using the A7R34 antibody in flow cytometry, immunofluorescence, or other cellular assays provides valuable insights into the behavior and function of CD127-expressing cells in the immune system. This precision tool is a must-have for studies focusing on T cell biology, lymphoid development, and immune regulation in mouse models.With its exceptional performance and reliability, the Mouse CD127 IL-7RA Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) - A7R34 (AGEL0743) is an essential asset for researchers seeking to deepen their understanding of immune responses and lymphocyte biology in mouse models.
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16872
Gene ID:
16197
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.