PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0750)

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SKU:
AGEL0750
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 (IL-7Ra) Monoclonal Antibody (PE/Cyanine7 Conjugated, A7R34) - AGEL0750 is a specialized tool for research involving the CD127 receptor, also known as IL-7Ra, a crucial protein involved in immune cell development and function. This monoclonal antibody, conjugated with PE/Cyanine7, is specifically designed for flow cytometry applications, enabling precise detection and analysis of CD127 expression on immune cells.CD127, a component of the IL-7 receptor complex, plays a pivotal role in lymphocyte survival, proliferation, and differentiation. Its expression pattern on various immune cell populations provides valuable insights into the immune system's dynamics and functionality.

By targeting CD127 with this unique antibody, researchers can explore the role of this receptor in immune responses, homeostasis, and diseases such as cancer, infectious diseases, and immunodeficiencies.The versatility of the Mouse CD127 (IL-7Ra) Monoclonal Antibody (PE/Cyanine7 Conjugated, A7R34) - AGEL0750 makes it an indispensable tool for immunologists, oncologists, and researchers studying immune regulation and related fields. Its high specificity and sensitivity ensure reliable results and facilitate in-depth investigations into the intricate mechanisms governing immune cell behavior and function.

Product Title:PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0750
Size:25µg, 100µg
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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