PE/Cyanine5 Anti-Mouse CD122 Antibody [5H4] (AGEL0794)

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SKU:
AGEL0794
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
5H4
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD122 Antibody [5H4]

The Mouse CD122 Monoclonal Antibody (PE-Cyanine5 Conjugated) - 5H4 (AGEL0794) is a highly specific and sensitive tool for researchers studying immune cells and cytokine receptors in mice. This antibody is designed to target CD122, also known as interleukin-2 receptor beta, a crucial component in the immune system that is involved in cell signaling and activation.With its PE-Cyanine5 conjugation, this monoclonal antibody offers the advantage of fluorescent detection, allowing for easy and efficient flow cytometry analysis of CD122 expression in various cell populations. The 5H4 clone has been rigorously validated for specificity and sensitivity, ensuring reliable and reproducible results in experimental settings.

By using the Mouse CD122 Monoclonal Antibody (PE-Cyanine5 Conjugated) - 5H4 (AGEL0794), researchers can gain valuable insights into the role of CD122 in immune responses, inflammation, and immune cell activation in mouse models. This antibody is an indispensable tool for furthering our understanding of immune regulation and can contribute to advancements in immunology, autoimmune disease research, and therapeutic development.

Product Title:PE/Cyanine5 Anti-Mouse CD122 Antibody [5H4]
SKU:AGEL0794
Size:50 Tests, 100 Tests, 200 Tests
Clone No:5H4
Synonyms:Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16297
Gene ID:16185
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

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