FITC Anti-Mouse CD122 Antibody [5H4] (AGEL0799)

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SKU:
AGEL0799
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Mouse CD122 Antibody [5H4]

The Mouse CD122 Monoclonal Antibody (FITC-conjugated 5H4) is a cutting-edge tool designed for researchers studying CD122, a critical cell surface receptor involved in immune cell function. This monoclonal antibody, labeled with FITC for fluorescent detection, offers high specificity and sensitivity for detecting CD122 in mouse samples, making it an invaluable asset for immunology and cell biology studies.CD122, also known as the Interleukin-2 receptor beta chain, plays a pivotal role in the regulation of immune responses by binding to interleukin-2 (IL-2) and modulating T cell activation and proliferation. The precise targeting of CD122 is essential for investigating immune signaling pathways and understanding the mechanisms underlying immune system function.

With its FITC conjugation, the 5H4 monoclonal antibody allows for convenient and reliable detection of CD122 in flow cytometry, immunofluorescence, and other fluorescence-based assays. Researchers can confidently explore the expression and function of CD122 in various cell types and experimental models, advancing their research in immunology, vaccine development, and autoimmune disease studies.Enhance your research capabilities with the Mouse CD122 Monoclonal Antibody (FITC-conjugated 5H4) and gain deeper insights into the intricate roles of CD122 in immune regulation and cellular signaling pathways. Stay at the forefront of scientific discovery with this powerful research tool from AssayGenie.

Product Title:FITC Anti-Mouse CD122 Antibody [5H4]
SKU:AGEL0799
Size:25µg, 100µg
Clone No:5H4
Synonyms:Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P16297
Gene ID:16185
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

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