APC Anti-Mouse CD122 Antibody [5H4] (AGEL0793)

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SKU:
AGEL0793
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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APC Anti-Mouse CD122 Antibody [5H4]

The Mouse CD122 Monoclonal Antibody (APC conjugated) - 5H4 (AGEL0793) offered by AssayGenie is a powerful tool for researchers studying immune responses in mouse models. This antibody specifically targets CD122, a vital cell surface receptor involved in the regulation of immune cell function and activation.CD122, also known as the IL-2 receptor beta chain, is essential for the signaling and growth of certain immune cells, particularly T cells. By binding to CD122, the 5H4 monoclonal antibody enables researchers to detect and analyze the expression of this important receptor in various cells, providing valuable insights into immune system dynamics and responses.

With its APC conjugation, this antibody is optimized for flow cytometry applications, allowing for precise and efficient quantification of CD122 expression on different cell populations. Whether investigating immune cell activation, differentiation, or function, the Mouse CD122 Monoclonal Antibody (APC conjugated) - 5H4 (AGEL0793) is a reliable reagent for advancing research in immunology, infectious diseases, and autoimmune disorders.

Product Title:APC Anti-Mouse CD122 Antibody [5H4]
SKU:AGEL0793
Size:50 Tests, 100 Tests, 200 Tests
Clone No:5H4
Synonyms:Interleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta; IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16297
Gene ID:16185
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

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