The Mouse CD11c Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated, N418) is a highly specific reagent designed for flow cytometry applications in immunology research. This antibody, available from AssayGenie, is meticulously validated for its binding affinity to the CD11c protein, a key marker for dendritic cells.Dendritic cells are vital players in the immune system, acting as antigen-presenting cells that initiate and regulate immune responses. The N418 antibody, conjugated with PERCP-Cyanine5.5, provides researchers with a robust tool for identifying and analyzing CD11c-expressing dendritic cells in various biological samples.
With high sensitivity and specificity, this antibody enables precise detection and quantification of CD11c-positive cells, facilitating detailed investigations into immune responses, vaccine development, and immune cell interactions. Its reliability and performance make it an essential component in studies related to immunotherapy, infectious diseases, and inflammatory conditions.Invest in the Mouse CD11c Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated, N418) from AssayGenie for accurate and reproducible flow cytometry analyses, advancing your research in immunology and related fields.
Product Title:
PerCP/Cyanine5.5 Anti-Mouse CD11c Antibody [N418]
SKU:
AGEL0520
Size:
25µg, 100µg
Clone No:
N418
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.