PE/Cyanine7 Anti-Mouse CD11c Antibody [N418] (AGEL0509)

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SKU:
AGEL0509
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
N418
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody (PE/Cyanine7 Conjugated, N418) is a specialized tool for immunology and cell biology studies. This antibody is designed for specific detection of the CD11c marker, a key cell surface molecule that plays a critical role in the function of dendritic cells.Dendritic cells are crucial players in the immune system, acting as antigen-presenting cells that initiate and regulate immune responses. The CD11c marker is commonly used to identify and isolate dendritic cells in various tissues. This high-quality monoclonal antibody, conjugated with PE/Cyanine7, allows for sensitive and precise detection of CD11c-expressing cells by flow cytometry.

By targeting CD11c, researchers can investigate the function and behavior of dendritic cells in different experimental systems. This antibody is validated for use in flow cytometry applications, providing reliable results for studies on immune responses, inflammation, antigen presentation, and immune cell interactions.In summary, the Mouse CD11c Monoclonal Antibody (PE/Cyanine7 Conjugated, N418) is a valuable tool for researchers interested in understanding the role of dendritic cells in immune regulation and inflammatory processes. Its specificity and sensitivity make it an essential reagent for a wide range of research applications in immunology and related fields.

Product Title:PE/Cyanine7 Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0509
Size:50 Tests, 100 Tests, 200 Tests
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Cyanine7 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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