PE/Cyanine5 Anti-Mouse CD11c Antibody [N418] (AGEL0517)

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SKU:
AGEL0517
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
N418
Conjugation:
PE/Cy5
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody PE/Cyanine5 Conjugated (clone N418, AGEL0517) offered by AssayGenie is a valuable tool for researchers studying immune cells expressing the CD11c marker. This antibody, derived from a monoclonal source, has been specifically conjugated with PE/Cyanine5 for enhanced detection in flow cytometry and fluorescence microscopy applications.CD11c is a marker commonly found on dendritic cells, a crucial component of the immune system involved in antigen presentation and immune response regulation. The N418 clone of this antibody is well-characterized and known for its high specificity and sensitivity in detecting CD11c-expressing cells in various tissues and biological samples.With its PE/Cyanine5 conjugation, this antibody allows for multicolor flow cytometry experiments and provides researchers with a powerful tool for studying dendritic cell populations in different immune contexts.

Its reliable performance and consistent results make it an essential component in immunology research, particularly in investigations related to immune cell subsets, inflammation, and immune system regulation.By utilizing the Mouse CD11c Monoclonal Antibody PE/Cyanine5 Conjugated (clone N418, AGEL0517) from AssayGenie, researchers can gain valuable insights into the role of CD11c-expressing cells in immune responses, paving the way for advancements in vaccine development, autoimmune disease studies, and immunotherapy research.

Product Title:PE/Cyanine5 Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0517
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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