The Mouse CD11c Monoclonal Antibody (PE/Cyanine5.5) is a specialized tool for researchers studying immune cells expressing the CD11c marker, commonly found on dendritic cells. This antibody, clone N418, is conjugated to PE/Cyanine5.5 for fluorescence detection and flow cytometry applications, allowing for precise identification and analysis of CD11c-positive cell populations.CD11c is a crucial cell surface marker involved in antigen presentation, immune response regulation, and inflammatory processes. By targeting CD11c with this monoclonal antibody, researchers can gain insights into the function and behavior of dendritic cells, aiding in the understanding of immune system mechanisms and their role in various diseases and conditions.
Ideal for immunology research, vaccine development, and immune cell profiling, the Mouse CD11c Monoclonal Antibody (PE/Cyanine5.5) provides reliable and specific detection of CD11c-expressing cells in experimental settings. Unlock the potential of your studies by incorporating this antibody into your research protocols for enhanced precision and accuracy in characterizing immune cell populations.
Product Title:
PE/Cyanine5.5 Anti-Mouse CD11c Antibody [N418]
SKU:
AGEL0510
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
N418
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
PE/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.