GenieFluor 488 Anti-Mouse CD11c Antibody [N418] (AGEL0521)

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SKU:
AGEL0521
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
N418
Conjugation:
AF 488
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody (AF488 conjugated, N418) is a vital tool for researchers investigating immune cells expressing CD11c, a key marker for dendritic cells. This monoclonal antibody, conjugated with AF488 for fluorescence applications, offers high specificity and sensitivity in detecting CD11c in mouse samples. Validated for use in flow cytometry and immunofluorescence, this antibody enables precise identification and analysis of CD11c-expressing cells in various tissues and experimental conditions.Dendritic cells, marked by the CD11c antigen, play a crucial role in initiating immune responses and regulating immune tolerance.

Understanding the function and distribution of CD11c-expressing dendritic cells is essential for studying immune system dynamics, inflammatory responses, and antigen presentation processes. This monoclonal antibody provides researchers with a reliable tool to delve into the complexities of dendritic cell biology and explore their implications in immunology, vaccine development, and autoimmune diseases.

Product Title:GenieFluor 488 Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0521
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 488 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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