GenieFluor 647 Anti-Mouse CD11a Antibody [FD441.8] (AGEL0839)

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SKU:
AGEL0839
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
FD441.8
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody (AF647 Conjugated) (FD441.8) is a specialized tool for researchers investigating cell adhesion and immune responses in mice. This monoclonal antibody is conjugated with AF647 for fluorescent detection, allowing for precise visualization and analysis of CD11a expression in various experimental settings.CD11a, also known as integrin alpha L, is a key component of lymphocyte function-associated antigen 1 (LFA-1), an adhesion molecule essential for activities such as leukocyte migration and T cell activation. By targeting CD11a with this specific antibody, researchers can gain insights into the role of LFA-1-mediated cell interactions in immune cell signaling, inflammation, and disease pathology in murine models.

This antibody is rigorously validated for specificity and sensitivity in assays such as flow cytometry and immunofluorescence, ensuring reliable results in mouse samples. Its ability to selectively bind to CD11a makes it an indispensable tool for studies focusing on immune cell behavior, inflammatory processes, and therapeutic interventions targeting integrin-mediated functions.With the Mouse CD11a Monoclonal Antibody (AF647 Conjugated) (FD441.8), researchers can delve deeper into the mechanisms underlying immune responses in mice, paving the way for advancements in immunology, inflammation research, and the development of novel treatments for immune-related disorders.

Product Title:GenieFluor 647 Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0839
Size:25µg, 100µg
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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