PE Anti-Mouse CD119 Antibody [GR-20] (AGEL1439)

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SKU:
AGEL1439
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE Anti-Mouse CD119 Antibody [GR-20]

The Mouse CD119 Monoclonal Antibody PE Conjugated (GR-20) is a cutting-edge tool designed for researchers investigating the CD119 molecule in immune regulation. CD119, also known as the Granulocyte receptor 20 (GR-20), is involved in immune responses and cell signaling pathways. This monoclonal antibody, conjugated with PE for enhanced detection capabilities, is derived from mouse sources and exhibits high reactivity with mouse samples.Validated for use in various immunoassays and flow cytometry applications, the Mouse CD119 Monoclonal Antibody PE Conjugated (GR-20) specifically targets the CD119 protein, allowing for precise detection and analysis in diverse cell populations.

This feature makes it an invaluable asset for studies focused on immunology, inflammation, and related areas of research.By delving into the role of CD119 in immune regulation, researchers can uncover its implications in diseases such as autoimmune disorders, cancer, and inflammatory conditions. With its ability to facilitate the study of immune responses and cellular interactions, this antibody serves as a key component in advancing our understanding of immune system functions and developing potential therapeutic interventions.

Product Title:PE Anti-Mouse CD119 Antibody [GR-20]
SKU:AGEL1439
Size:25µg, 100µg
Clone No:GR-20
Synonyms:Interferon gamma receptor 1;Ifngr1;IFN-gamma-R1;IFN-gamma-R-alpha;CD119;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15261
Gene ID:15979
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

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