PE/Cyanine7 Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL1167)

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SKU:
AGEL1167
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD106 Antibody [M/K-2.7]

The Mouse CD106 Monoclonal Antibody PE/Cyanine7 Conjugated (M-K-2.7) is a cutting-edge research tool designed for the detection and analysis of CD106, also known as vascular cell adhesion molecule 1 (VCAM-1). This monoclonal antibody, conjugated with PE/Cyanine7, offers high specificity and sensitivity in binding with CD106, enabling precise visualization and measurement in various experimental settings.CD106 is a cell surface adhesion molecule that plays a crucial role in mediating interactions between vascular endothelial cells and immune cells, facilitating processes like leukocyte adhesion and transmigration. Its involvement in inflammation and immune response regulation makes it a key target for investigating various pathological conditions, including cardiovascular diseases, autoimmune disorders, and inflammatory conditions.

The Mouse CD106 Monoclonal Antibody PE/Cyanine7 Conjugated (M-K-2.7) provides researchers with a reliable tool for studying the expression and function of CD106 in different biological samples. Its conjugation with PE/Cyanine7 allows for multiparametric flow cytometry analysis, promoting detailed characterization of cellular populations expressing CD106. This antibody is an invaluable asset for studies in immunology, vascular biology, and inflammatory processes, offering insights into the role of CD106 in disease pathogenesis and potential therapeutic interventions.

Product Title:PE/Cyanine7 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL1167
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE/Cyanine7 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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