The Mouse CD106 Monoclonal Antibody PE-Cyanine5 Conjugated (M/K-2.7) (AGEL1166) is a powerful tool for researchers studying the role of CD106 in immune regulation and inflammation. CD106, also known as VCAM-1, is a cell adhesion molecule that plays a crucial role in immune responses and inflammatory processes.This monoclonal antibody, conjugated with PE-Cyanine5, specifically targets CD106 in mouse samples, allowing for accurate detection and analysis in flow cytometry experiments. Its high reactivity and specificity make it an ideal tool for studies in immunology, cancer research, and inflammatory conditions.
By targeting CD106, researchers can gain valuable insights into the molecular mechanisms underlying immune responses and inflammation, paving the way for the development of novel therapeutic strategies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. The Mouse CD106 Monoclonal Antibody PE-Cyanine5 Conjugated (M/K-2.7) (AGEL1166) is a valuable asset for research aimed at understanding and targeting CD106 in various disease settings.
Product Title:
PE/Cyanine5 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:
AGEL1166
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
M/K-2.7
Synonyms:
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
PE/Cyanine5 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).