Purified Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL0334)

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SKU:
AGEL0334
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG1
Clone:
M/K-2.7
Conjugation:
Unconjugated
Applications:
IF
Frequently bought together:

Description

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Purified Anti-Mouse CD106 Antibody [M/K-2.7]

The Mouse CD106 Monoclonal Antibody (M/K-2.7) is a powerful tool for researchers investigating cellular adhesion molecules, specifically CD106, also known as vascular cell adhesion molecule 1 (VCAM-1). This monoclonal antibody, produced using hybridoma technology, exhibits high specificity and sensitivity towards mouse samples, making it ideal for a variety of experimental applications.CD106, a transmembrane glycoprotein, is a key player in the immune response and inflammation processes by mediating leukocyte adhesion and extravasation. Its expression is upregulated in response to inflammatory stimuli, indicating its crucial role in immune cell recruitment and activation at sites of inflammation. By targeting CD106 with this monoclonal antibody, researchers can accurately detect and quantify the expression levels of CD106 in different cell types and tissues.

This antibody is suitable for immunofluorescence, immunohistochemistry, and flow cytometry assays, enabling detailed visualization and analysis of CD106 expression patterns and localization. Understanding the role of CD106 in immune cell adhesion and interaction can provide valuable insights into various pathophysiological processes, including inflammatory diseases, atherosclerosis, and autoimmune disorders.By using the Mouse CD106 Monoclonal Antibody (M/K-2.7), researchers can advance their studies in immunology, vascular biology, and related fields, ultimately contributing to a better understanding of the mechanisms underlying immune responses and inflammatory conditions.

Product Title:Purified Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL0334
Size:25µg, 100µg
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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