FITC Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL1172)

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SKU:
AGEL1172
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M/K-2.7
Conjugation:
FITC
Frequently bought together:

Description

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FITC Anti-Mouse CD106 Antibody [M/K-2.7]

The Mouse CD106 Monoclonal Antibody (FITC-conjugated, M/K-2.7) offered by Assay Genie (AGEL1172) is a vital tool for research involving CD106, a cell surface molecule commonly known as VCAM-1. This monoclonal antibody, derived from mouse cells, is specifically designed for use in flow cytometry applications, making it ideal for the detection and analysis of VCAM-1 in various cell types.VCAM-1 is a crucial adhesion molecule that plays a pivotal role in immune responses, particularly in the recruitment of leukocytes to sites of inflammation. Its involvement in processes like cell adhesion and migration makes it a key target for research in immunology, inflammation, and vascular biology.

By utilizing the Mouse CD106 Monoclonal Antibody, researchers can gain valuable insights into the role of VCAM-1 in different physiological and pathological conditions, including atherosclerosis, inflammation, and autoimmune diseases.Investigating the expression and function of VCAM-1 with this highly reactive and validated monoclonal antibody can provide essential information for understanding the mechanisms underlying immune responses and inflammatory processes. Researchers interested in studying the complex interplay of adhesion molecules in health and disease will find the Mouse CD106 Monoclonal Antibody to be a valuable asset in their experimental endeavors.

Product Title:FITC Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL1172
Size:25µg, 100µg
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:FITC Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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