Mouse Biglycan/BGN Recombinant Protein (RPES4649)
- SKU:
- RPES4649
- Product type:
- Recombinant Protein
- Host species:
- HEK293 Cells
- Reactivity:
- Mouse
Frequently bought together:
Description
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Mouse Biglycan/BGN Recombinant Protein
Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
| Product Name: | Mouse Biglycan/BGN Recombinant Protein (RPES4649) |
| Product Code: | RPES4649 |
| Size: | 50µg |
| Species: | Mouse |
| Expressed Host: | HEK293 Cells |
| Synonyms: | BG,DSPG1,PG-S1,PGI,SLRR1A |
| Accession: | NP_031568.2 |
| Sequence: | Met1-Lys369 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Purity: | > 85 % as determined by SDS-PAGE |
| Mol Mass: | 66.5 kDa |
| AP Mol Mass: | 67 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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