Mouse ALDOC Recombinant Protein (RPPB1396)

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SKU:
RPPB1396
Product type:
Recombinant Protein
Size:
20ug
Species:
Mouse
Target:
ALDOC
Synonyms:
Aldolase 3
Synonyms:
Brain-type aldolase
Synonyms:
Scrapie-responsive protein 2
Synonyms:
Zebrin II
Source:
Escherichia Coli
Uniprot:
P05063
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Description

Product Name:Mouse ALDOC Recombinant Protein
Product Code:RPPB1396
Size:20µg
Species:Mouse
Target:ALDOC
Synonyms:Aldolase 3, Brain-type aldolase, Scrapie-responsive protein 2, Zebrin II, Aldo3, Scrg2, Fructose-bisphosphate aldolase C, ALDOC.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear colorless solution.
Formulation:The ALDOC solution (1mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMPHSYP ALSAEQKKEL SDIALRIVTP GKGILAADES VGSMAKRLSQ IGVENTEENR RLYRQVLFSA DDRVKKCIGG VIFFHETLYQ KDDNGVPFVR TIQDKGILVG IKVDKGVVPL AGTDGETTTQ GLDGLLERCA QYKKDGADFA KWRCVLKISD RTPSALAILE NANVLARYAS ICQQNGIVPI VEPEILPDGD HDLKRCQYVT EKVLAAVYKA LSDHHVYLEG TLLKPNMVTP GHACPIKYSP EEIAMATVTA LRRTVPPAVP GVTFLSGGQS EEEASLNLNA INRCPLPRPW ALTFSYGRAL QASALNAWRG QRDNAGAATE EFIKRAEMNG LAAQGRYEGS GDGGAAAQSL YIANHAY

Aldolase C Fructose-Bisphosphate (ALDOC) belongs to the class I fructose-bisphosphate aldolase family. ALDOC is a glycolytic enzyme which catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. ALDOC is expressed exclusively in the hippocampus and Purkinje cells of the brain.

ALDOC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 387 amino acids (1-363 a.a) and having a molecular mass of 41.9kDa.ALDOC is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Lyase; EC 4.1.2.13; Carbohydrate Metabolism - fructose and mannoseCellular Component: mitochondrion; axon; cytoplasmMolecular Function: cytoskeletal protein binding; lyase activity; fructose-bisphosphate aldolase activity; catalytic activityBiological Process: fructose 1,6-bisphosphate metabolic process; glycolysis; apoptosis; protein heterotetramerization; aging; protein homotetramerization
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the aldolase family of enzymes that is mainly expressed in neuronal tissues. The encoded protein is an enzyme of the glycolysis pathway, and catalyzes the conversion of fructose-1,6-bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
UniProt Code:P05063
NCBI GenInfo Identifier:742670581
NCBI Gene ID:11676
NCBI Accession:NP_001290352.1
UniProt Secondary Accession:P05063,Q64011, Q8CA91, Q99K96, Q9DBA4, Q9JK32
UniProt Related Accession:P05063
Molecular Weight:39,395 Da
NCBI Full Name:fructose-bisphosphate aldolase C
NCBI Synonym Full Names:aldolase C, fructose-bisphosphate
NCBI Official Symbol:Aldoc  
NCBI Official Synonym Symbols:Aldo3; Scrg2; AI847350; AU040929  
NCBI Protein Information:fructose-bisphosphate aldolase C
UniProt Protein Name:Fructose-bisphosphate aldolase C
UniProt Synonym Protein Names:Aldolase 3; Brain-type aldolase; Scrapie-responsive protein 2; Zebrin II
Protein Family:Fructose-bisphosphate aldolase
UniProt Gene Name:Aldoc  
UniProt Entry Name:ALDOC_MOUSE
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