Mouse ALDOC Recombinant Protein (RPPB1396)
- SKU:
- RPPB1396
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Mouse
- Target:
- ALDOC
- Synonyms:
- Aldolase 3
- Brain-type aldolase
- Scrapie-responsive protein 2
- Zebrin II
- Source:
- Escherichia Coli
- Uniprot:
- P05063
Frequently bought together:
Description
| Product Name: | Mouse ALDOC Recombinant Protein |
| Product Code: | RPPB1396 |
| Size: | 20µg |
| Species: | Mouse |
| Target: | ALDOC |
| Synonyms: | Aldolase 3, Brain-type aldolase, Scrapie-responsive protein 2, Zebrin II, Aldo3, Scrg2, Fructose-bisphosphate aldolase C, ALDOC. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear colorless solution. |
| Formulation: | The ALDOC solution (1mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMPHSYP ALSAEQKKEL SDIALRIVTP GKGILAADES VGSMAKRLSQ IGVENTEENR RLYRQVLFSA DDRVKKCIGG VIFFHETLYQ KDDNGVPFVR TIQDKGILVG IKVDKGVVPL AGTDGETTTQ GLDGLLERCA QYKKDGADFA KWRCVLKISD RTPSALAILE NANVLARYAS ICQQNGIVPI VEPEILPDGD HDLKRCQYVT EKVLAAVYKA LSDHHVYLEG TLLKPNMVTP GHACPIKYSP EEIAMATVTA LRRTVPPAVP GVTFLSGGQS EEEASLNLNA INRCPLPRPW ALTFSYGRAL QASALNAWRG QRDNAGAATE EFIKRAEMNG LAAQGRYEGS GDGGAAAQSL YIANHAY |
Aldolase C Fructose-Bisphosphate (ALDOC) belongs to the class I fructose-bisphosphate aldolase family. ALDOC is a glycolytic enzyme which catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. ALDOC is expressed exclusively in the hippocampus and Purkinje cells of the brain.
ALDOC Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 387 amino acids (1-363 a.a) and having a molecular mass of 41.9kDa.ALDOC is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Lyase; EC 4.1.2.13; Carbohydrate Metabolism - fructose and mannoseCellular Component: mitochondrion; axon; cytoplasmMolecular Function: cytoskeletal protein binding; lyase activity; fructose-bisphosphate aldolase activity; catalytic activityBiological Process: fructose 1,6-bisphosphate metabolic process; glycolysis; apoptosis; protein heterotetramerization; aging; protein homotetramerization |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the aldolase family of enzymes that is mainly expressed in neuronal tissues. The encoded protein is an enzyme of the glycolysis pathway, and catalyzes the conversion of fructose-1,6-bisphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| UniProt Code: | P05063 |
| NCBI GenInfo Identifier: | 742670581 |
| NCBI Gene ID: | 11676 |
| NCBI Accession: | NP_001290352.1 |
| UniProt Secondary Accession: | P05063,Q64011, Q8CA91, Q99K96, Q9DBA4, Q9JK32 |
| UniProt Related Accession: | P05063 |
| Molecular Weight: | 39,395 Da |
| NCBI Full Name: | fructose-bisphosphate aldolase C |
| NCBI Synonym Full Names: | aldolase C, fructose-bisphosphate |
| NCBI Official Symbol: | Aldoc |
| NCBI Official Synonym Symbols: | Aldo3; Scrg2; AI847350; AU040929 |
| NCBI Protein Information: | fructose-bisphosphate aldolase C |
| UniProt Protein Name: | Fructose-bisphosphate aldolase C |
| UniProt Synonym Protein Names: | Aldolase 3; Brain-type aldolase; Scrapie-responsive protein 2; Zebrin II |
| Protein Family: | Fructose-bisphosphate aldolase |
| UniProt Gene Name: | Aldoc |
| UniProt Entry Name: | ALDOC_MOUSE |
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