Mouse AHSG Recombinant Protein (RPPB2720)
- SKU:
- RPPB2720
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Mouse
- Target:
- AHSG
- Synonyms:
- Alpha-2-HS-glycoprotein
- Countertrypin
- Fetuin-A
- Source:
- Sf9 Insect cells
- Uniprot:
- P29699
Description
| Product Name: | Mouse AHSG Recombinant Protein |
| Product Code: | RPPB2720 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | AHSG |
| Synonyms: | Alpha-2-HS-glycoprotein, Countertrypin, Fetuin-A. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | AHSG protein solution (0.25mg/ml) contains phosphatebuffered saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrierprotein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | APQGTGLGFR ELACDDPEAE QVALLAVDYL NNHLLQGFKQ VLNQIDKVKVWSRRPFGVVY EMEVDTLETT CHALDPTPLA NCSVRQLTEH AVEGDCDFHI LKQDGQFRVM HTQCHSTPDSAEDVRKLCPR CPLLTPFNDT NVVHTVNTAL AAFNTQNNGT YFKLVEISRA QNVPLPVSTL VEFVIAATDCTAKEVTDPAK CNLLAEKQHG FCKANLMHNL GGEEVSVACK LFQTQPQPAN ANAVGPVPTA NAALPADPPASVVVGPVVVP RGLSDHRTYH DLRHAFSPVA SVESASGETL HSPKVGQPGA AGPVSPMCPG RIRHFKIHHHHHH |
AHSG (fetuin-A) which is a glycoprotein present in the serum, is synthesized by hepatocytes. AHSG is one of the fetuin class of plasma binding proteins. It is involved in a number of functions, such as endocytosis, brain development and the formation of bone tissue. It is usually present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, hence it has been postulated that it participates in the development of the tissues. Yet, its exact significance is still vague. AHSG promotes endocytosis, hold opsonic properties and influences the mineral phase of the bone. Affinity for calcium and barium ions has been shown.
AHSG produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 333 amino acids (19-345.a.) and having a molecular mass of 36.1kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).AHSG is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Probably involved in differentiation. |
| UniProt Code: | P29699 |
| NCBI GenInfo Identifier: | 7304875 |
| NCBI Gene ID: | 11625 |
| NCBI Accession: | NP_038493.1 |
| UniProt Secondary Accession: | P29699,O35634, |
| UniProt Related Accession: | P29699 |
| Molecular Weight: | 37,326 Da |
| NCBI Full Name: | alpha-2-HS-glycoprotein isoform 1 |
| NCBI Synonym Full Names: | alpha-2-HS-glycoprotein |
| NCBI Official Symbol: | Ahsg |
| NCBI Protein Information: | alpha-2-HS-glycoprotein |
| UniProt Protein Name: | Alpha-2-HS-glycoprotein |
| UniProt Synonym Protein Names: | Countertrypin; Fetuin-A |
| Protein Family: | Alpha-2-HS-glycoprotein |
| UniProt Gene Name: | Ahsg |
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