Monkey GM CSF Recombinant Protein (RPPB0359)
- SKU:
- RPPB0359
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Monkey
- Target:
- GM CSF
- Synonyms:
- CSF-2
- MGI-1GM
- GM-CSF
- Pluripoietin-alpha
- Source:
- Escherichia Coli
- Uniprot:
- Q0MUT8
Description
| Product Name: | Monkey GM CSF Recombinant Protein |
| Product Code: | RPPB0359 |
| Size: | 10µg |
| Species: | Monkey |
| Target: | GM CSF |
| Synonyms: | CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, MGC131935, MGC138897. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | GM-CSF was lyophilized from a concentrated (1mg/ml) solution containing 1x PBS pH 7.4. |
| Solubility: | It is recommended to reconstitute the lyophilized GMCSF in sterile 18M?-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized GMCSF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GMCSF should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 98.0% as determined by SDS-PAGE and RP-HPLC. |
| Amino Acid Sequence: | APARSPSPGT QPWEHVNAIQ EARRLLNLSR DTAAEMNKTV EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQE |
| Biological Activity: | The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1ng/ml, corresponding to a specific activity of > 10,000,000 IU/mg. |
| UniProt Code: | Q0MUT8 |
GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Granulocyte Macrophage Colony Stimulating Factor Monkey Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 127 amino acids and having a molecular mass of 14.4 kDa.GM-CSF is purified by proprietary chromatographic techniques.
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