MIA2 Antibody (PACO56026)
- SKU:
- PACO56026
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MIA2 Antibody (PACO56026) |
Antibody SKU: | PACO56026 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Melanoma inhibitory activity protein 2 protein (178-354AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO56026 diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
IHC image of PACO56026 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). |
Synonyms: | Melanoma inhibitory activity protein 2, MIA2 |
UniProt Protein Function: | MIA2: May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. Belongs to the MIA/OTOR family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 14q13.2Cellular Component: extracellular regionBiological Process: cholesterol homeostasis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q96PC5 |
NCBI GenInfo Identifier: | 308153584 |
NCBI Gene ID: | 117153 |
NCBI Accession: | Q96PC5.3 |
UniProt Secondary Accession: | Q96PC5,Q9H6C1, A1L4H0 |
UniProt Related Accession: | Q96PC5 |
Molecular Weight: | 74,089 Da |
NCBI Full Name: | Melanoma inhibitory activity protein 2 |
NCBI Synonym Full Names: | melanoma inhibitory activity 2 |
NCBI Official Symbol: | MIA2 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | melanoma inhibitory activity protein 2 |
UniProt Protein Name: | Melanoma inhibitory activity protein 2 |
UniProt Synonym Protein Names: | |
Protein Family: | |
UniProt Gene Name: | MIA2 |
UniProt Entry Name: | MIA2_HUMAN |
Antibodies | ELISA Kits |
MIA2 Antibody (PACO02434) | Human Melanoma inhibitory activity protein 2 (MIA2) ELISA Kit |
MIA2 Antibody (PACO07267) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |