Lypla1 Antibody (PACO28090)
- SKU:
- PACO28090
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Lypla1 Antibody (PACO28090) |
| Antibody SKU: | PACO28090 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of Hela cells using PACO28090 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Hydrolyzes fatty acid, from S-acylated cysteine residues in proteins such as trimeric G α proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity. |
| Synonyms: | Acyl-protein thioesterase 1 (APT-1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I), Lypla1, Apt1 Pla1a |
| UniProt Protein Function: | LYPLA1: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Belongs to the AB hydrolase 2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.1.2.-; Lipid Metabolism - glycerophospholipid; Mitochondrial; PhospholipaseChromosomal Location of Human Ortholog: 1|1 A1Cellular Component: cytosol; mitochondrionMolecular Function: lipase activity; lysophospholipase activity; palmitoyl-(protein) hydrolase activityBiological Process: negative regulation of Golgi to plasma membrane protein transport; protein depalmitoylation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P97823 |
| NCBI GenInfo Identifier: | 6678760 |
| NCBI Gene ID: | 18777 |
| NCBI Accession: | NP_032892.1 |
| UniProt Secondary Accession: | P97823,Q3TJZ0, Q7TPX1, Q8BWM6 |
| UniProt Related Accession: | P97823 |
| Molecular Weight: | 52.1kD |
| NCBI Full Name: | acyl-protein thioesterase 1 |
| NCBI Synonym Full Names: | lysophospholipase 1 |
| NCBI Official Symbol: | Lypla1 |
| NCBI Official Synonym Symbols: | Pla1a |
| NCBI Protein Information: | acyl-protein thioesterase 1 |
| UniProt Protein Name: | Acyl-protein thioesterase 1 |
| UniProt Synonym Protein Names: | Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I |
| Protein Family: | Acyl-protein thioesterase |
| UniProt Gene Name: | Lypla1 |
| UniProt Entry Name: |
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