KRTAP8-1 Antibody (PACO37774)
- SKU:
- PACO37774
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | KRTAP8-1 Antibody (PACO37774) |
| Antibody SKU: | PACO37774 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Keratin-associated protein 8-1 protein (1-63AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO37774 at dilution of 1:100. |
| Background: | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Synonyms: | Keratin-associated protein 8-1 (High glycine-tyrosine keratin-associated protein 8.1), KRTAP8-1, KAP8.1 KRTAP8.1 |
| UniProt Protein Function: | KRTAP8-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 8 family.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: intermediate filament |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IUC2 |
| NCBI GenInfo Identifier: | 28466975 |
| NCBI Gene ID: | 337879 |
| NCBI Accession: | NP_787053.1 |
| UniProt Secondary Accession: | Q8IUC2,Q3LI57 |
| UniProt Related Accession: | Q8IUC2 |
| Molecular Weight: | 7 kDa (MW of target protein) |
| NCBI Full Name: | keratin-associated protein 8-1 |
| NCBI Synonym Full Names: | keratin associated protein 8-1 |
| NCBI Official Symbol: | KRTAP8-1 |
| NCBI Official Synonym Symbols: | KAP8.1 |
| NCBI Protein Information: | keratin-associated protein 8-1 |
| UniProt Protein Name: | Keratin-associated protein 8-1 |
| UniProt Synonym Protein Names: | High glycine-tyrosine keratin-associated protein 8.1 |
| Protein Family: | |
| UniProt Gene Name: | KRTAP8-1 |
| UniProt Entry Name: | KRA81_HUMAN |
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