KRTAP3-2 Antibody (PACO41014)
- SKU:
- PACO41014
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | KRTAP3-2 Antibody (PACO41014) |
| Antibody SKU: | PACO41014 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Keratin-associated protein 3-2 protein (2-98AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO41014 at dilution of 1:100. |
| Background: | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Synonyms: | Keratin-associated protein 3-2 (High sulfur keratin-associated protein 3.2) (Keratin-associated protein 3.2), KRTAP3-2, KAP3.2 KRTAP3.2 |
| UniProt Protein Function: | KRTAP3-2: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 3 family.Chromosomal Location of Human Ortholog: 17q21.2Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BYR7 |
| NCBI GenInfo Identifier: | 21961309 |
| NCBI Gene ID: | 83897 |
| NCBI Accession: | BC034582 |
| UniProt Secondary Accession: | Q9BYR7 |
| UniProt Related Accession: | Q9BYR7 |
| Molecular Weight: | 10,407 Da |
| NCBI Full Name: | Homo sapiens keratin associated protein 3-2, mRNA |
| NCBI Synonym Full Names: | keratin associated protein 3-2 |
| NCBI Official Symbol: | KRTAP3-2 |
| NCBI Official Synonym Symbols: | KAP3.2; KRTAP3.2 |
| NCBI Protein Information: | keratin-associated protein 3-2 |
| UniProt Protein Name: | Keratin-associated protein 3-2 |
| UniProt Synonym Protein Names: | High sulfur keratin-associated protein 3.2; Keratin-associated protein 3.2 |
| Protein Family: | |
| UniProt Gene Name: | KRTAP3-2 |
| UniProt Entry Name: | KRA32_HUMAN |
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