| UniProt Protein Function: | KRTAP3-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 3 family.Chromosomal Location of Human Ortholog: 17q21.2Cellular Component: keratin filamentMolecular Function: structural molecule activity |
| UniProt Protein Details: | |
| NCBI Summary: | This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BYR8 |
| NCBI GenInfo Identifier: | 13994362 |
| NCBI Gene ID: | 83896 |
| NCBI Accession: | NP_114164.1 |
| UniProt Secondary Accession: | Q9BYR8,Q14DM4 |
| UniProt Related Accession: | Q9BYR8 |
| Molecular Weight: | 10,539 Da |
| NCBI Full Name: | keratin-associated protein 3-1 |
| NCBI Synonym Full Names: | keratin associated protein 3-1 |
| NCBI Official Symbol: | KRTAP3-1 |
| NCBI Official Synonym Symbols: | KAP3.1; KRTAP3.1 |
| NCBI Protein Information: | keratin-associated protein 3-1; high sulfur keratin-associated protein 3.1 |
| UniProt Protein Name: | Keratin-associated protein 3-1 |
| UniProt Synonym Protein Names: | High sulfur keratin-associated protein 3.1; Keratin-associated protein 3.1 |
| Protein Family: | Keratin-associated protein |
| UniProt Gene Name: | KRTAP3-1 |
| UniProt Entry Name: | KRA31_HUMAN |
