| UniProt Protein Function: | KLRF1: Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Receptor, misc.; Membrane protein, integralChromosomal Location of Human Ortholog: 12p13.31Cellular Component: membrane; integral to plasma membraneMolecular Function: transmembrane receptor activity; MHC class I receptor activity; carbohydrate bindingBiological Process: cell surface receptor linked signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009] |
| UniProt Code: | Q9NZS2 |
| NCBI GenInfo Identifier: | 625180299 |
| NCBI Gene ID: | 51348 |
| NCBI Accession: | NP_001278751.1 |
| UniProt Secondary Accession: | Q9NZS2,Q4KMT5, Q96PR2, Q96PR3, Q9NZS1 |
| UniProt Related Accession: | Q9NZS2 |
| Molecular Weight: | 27kDa |
| NCBI Full Name: | killer cell lectin-like receptor subfamily F member 1 isoform KLRF1-s |
| NCBI Synonym Full Names: | killer cell lectin-like receptor subfamily F, member 1 |
| NCBI Official Symbol: | KLRF1 |
| NCBI Official Synonym Symbols: | NKp80; CLEC5C |
| NCBI Protein Information: | killer cell lectin-like receptor subfamily F member 1 |
| UniProt Protein Name: | Killer cell lectin-like receptor subfamily F member 1 |
| UniProt Synonym Protein Names: | Activating coreceptor NKp80; C-type lectin domain family 5 member C |
| Protein Family: | Killer cell lectin-like receptor subfamily |
| UniProt Gene Name: | KLRF1 |
| UniProt Entry Name: | KLRF1_HUMAN |
