Klebsiella pneumoniae NEO Recombinant Protein (RPES3535)

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SKU:
RPES3535
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Klebsiella pneumoniae
Frequently bought together:

Description

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Klebsiella pneumoniae NEO Recombinant Protein

Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.

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