Klebsiella pneumoniae NEO Recombinant Protein (RPES3535)
- SKU:
- RPES3535
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Klebsiella pneumoniae
Frequently bought together:
Description
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Klebsiella pneumoniae NEO Recombinant Protein
Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
Product Name: | Klebsiella pneumoniae NEO Recombinant Protein (RPES3535) |
Product Code: | RPES3535 |
Size: | 10µg |
Species: | Klebsiella pneumoniae |
Expressed Host: | E.coli |
Synonyms: | Aminoglycoside 3'-phosphotransferase, APH(3')-II, APH(3')II, Kanamycin kinase type II, Neomycin-kanamycin phosphotransferase type II, neo |
Accession: | P00552 |
Sequence: | Met1-Phe264 |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Klebsiella pneumoniae NEO is produced by our E.coli expression system and the target gene encoding Met1-Phe264 is expressed. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 29 kDa |
AP Mol Mass: | 28-30 kDa |
Formulation: | Supplied as a 0.2 µm filtered solution of PBS, pH 7.4, 20% Glycerol. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |