Intermediate capsid protein VP6 Antibody (PACO35198)
- SKU:
- PACO35198
- Product type:
- Antibody
- Reactivity:
- Rotavirus A
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | Intermediate capsid protein VP6 Antibody (PACO35198) |
| Antibody SKU: | PACO35198 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rotavirus A |
| Immunogen: | Recombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP. |
| Synonyms: | Intermediate capsid protein VP6 |
| UniProt Protein Function: | Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | B1NKS8 |
| NCBI GenInfo Identifier: | 226698054 |
| NCBI Gene ID: | |
| NCBI Accession: | B1NKS8.1 |
| UniProt Secondary Accession: | B1NKS8,A3DSK7 |
| UniProt Related Accession: | B1NKS8 |
| Molecular Weight: | |
| NCBI Full Name: | Intermediate capsid protein VP6 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Intermediate capsid protein VP6 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | |
| UniProt Entry Name: | VP6_ROTHL |
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