IFT46 Antibody (PACO47074)
- SKU:
- PACO47074
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IFT46 Antibody (PACO47074) |
Antibody SKU: | PACO47074 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Intraflagellar transport protein 46 homolog protein (1-304AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: IFT46 antibody at 8 µg/ml + Mouse skeletal muscle tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 35, 41 kDa. Observed band size: 35 kDa.. | |
Immunohistochemistry of paraffin-embedded human melanoma using PACO47074 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO47074 at dilution of 1:100. |
Background: | Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity). |
Synonyms: | Intraflagellar transport protein 46 homolog, IFT46, C11orf2 C11orf60 |
UniProt Protein Function: | IFT46: Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis. Belongs to the IFT46 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11q23.3Cellular Component: centrosome; cytoplasm; motile primary cilium; ciliumMolecular Function: protein C-terminus bindingBiological Process: smoothened signaling pathway; protein stabilization; organelle organization and biogenesis; intraflagellar transport; cilium biogenesis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NQC8 |
NCBI GenInfo Identifier: | 281182834 |
NCBI Gene ID: | 56912 |
NCBI Accession: | NP_001162089.1 |
UniProt Secondary Accession: | Q9NQC8,Q9H6V5, A8K0F6 |
UniProt Related Accession: | Q9NQC8 |
Molecular Weight: | 40,064 Da |
NCBI Full Name: | intraflagellar transport protein 46 homolog isoform 2 |
NCBI Synonym Full Names: | intraflagellar transport 46 |
NCBI Official Symbol: | IFT46 |
NCBI Official Synonym Symbols: | CFAP32; C11orf2; C11orf60 |
NCBI Protein Information: | intraflagellar transport protein 46 homolog |
UniProt Protein Name: | Intraflagellar transport protein 46 homolog |
UniProt Synonym Protein Names: | |
Protein Family: | Intraflagellar transport protein |
UniProt Gene Name: | IFT46 |
UniProt Entry Name: | IFT46_HUMAN |