IFNLR1 Antibody (PACO01807)
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주문- SKU:
- PACO01807
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IFNLR1 Antibody |
Antibody SKU: | PACO01807 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human IL-28Ralpha. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | IL28RA; IFNLR1; LICR2; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; |
UniProt Protein Function: | IL28RA: The IL28RA/IL10RB dimer is a receptor for IL28A, IL28B and IL29. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the type II cytokine receptor family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: integral to membrane; interleukin-28 receptor complex Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding Biological Process: negative regulation of cell proliferation; mucosal immune response; cytokine and chemokine mediated signaling pathway; regulation of defense response to virus by host; defense response to virus |
NCBI Summary: | The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IU57 |
NCBI GenInfo Identifier: | 55976528 |
NCBI Gene ID: | 163702 |
NCBI Accession: | Q8IU57.1 |
UniProt Related Accession: | Q8IU57 |
Molecular Weight: | Observed MW: 57kDa |
NCBI Full Name: | Interferon lambda receptor 1 |
NCBI Synonym Full Names: | interferon lambda receptor 1 |
NCBI Official Symbol: | IFNLR1 |
NCBI Official Synonym Symbols: | IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1 |
NCBI Protein Information: | interferon lambda receptor 1 |
UniProt Protein Name: | Interferon lambda receptor 1 |
UniProt Synonym Protein Names: | Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Likely interleukin or cytokine receptor 2 |
UniProt Gene Name: | IFNLR1 |
UniProt Entry Name: | INLR1_HUMAN |