Human ZCCHC17 Recombinant Protein (RPPB5177)
- SKU:
- RPPB5177
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- ZCCHC17
- Synonyms:
- Zinc finger CCHC domain containing 17
- PS1D
- pNO40
- HSPC251
- Source:
- Escherichia Coli
- Uniprot:
- Q9NP64
Description
| Product Name: | Human ZCCHC17 Recombinant Protein |
| Product Code: | RPPB5177 |
| Size: | 10µg |
| Species: | Human |
| Target: | ZCCHC17 |
| Synonyms: | Zinc finger CCHC domain containing 17, PS1D, pNO40, HSPC251, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, RP11-266K22.1, Nucleolar protein of 40 kDa, PS1D protein. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The ZCCHC17 protein solution (0.25mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 100mM NaCl, 2mM DTT, 0.1mM PMSF and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNSGRPE TMENLPALYT IFQGEVAMVT DYGAFIKIPG CRKQGLVHRT HMSSCRVDKP SEIVDVGDKV WVKLIGREMK NDRIKVSLSM KVVNQGTGKD LDPNNVIIEQ EERRRRSFQD YTGQKITLEA VLNTTCKKCG CKGHFAKDCF MQPGGTKYSL IPDEEEEKEE AKSAEFEKPD PTRNPSRKRK KEKKKKKHRD RKSSDSDSSD SESDTGKRAR HTSKDSKAAK KKKKKKKHKK KHKE |
ZCCHC17 protein interacts with PNN and associates with the 60S ribosomal subunit. Universally expressed, ZCCHC17 is localizing to the nucleolus, and takes part in ribosome maturation and biogenesis.
ZCCHC17 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 264 amino acids (1-241a.a.) and having a molecular mass of 30.0 kDa (Molecular weight on SDS-PAGE will appear higher). ZCCHC17 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ZCCHC17: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; Ribosomal; RNA-binding Chromosomal Location of Human Ortholog: 1p35.2 Cellular Component: intermediate filament cytoskeleton; intracellular membrane-bound organelle; nucleolus; ribonucleoprotein complex; nucleus Molecular Function:protein binding; zinc ion binding |
| UniProt Code: | Q9NP64 |
| NCBI GenInfo Identifier: | 543173111 |
| NCBI Gene ID: | 51538 |
| NCBI Accession: | NP_001269495.1 |
| UniProt Related Accession: | Q9NP64 |
| Molecular Weight: | |
| NCBI Full Name: | nucleolar protein of 40 kDa isoform a |
| NCBI Synonym Full Names: | zinc finger CCHC-type containing 17 |
| NCBI Official Symbol: | ZCCHC17 |
| NCBI Official Synonym Symbols: | PS1D; pNO40; HSPC251 |
| NCBI Protein Information: | nucleolar protein of 40 kDa |
| UniProt Protein Name: | Nucleolar protein of 40 kDa |
| UniProt Synonym Protein Names: | Pnn-interacting nucleolar protein; Putative S1 RNA-binding domain protein; PS1D protein; Zinc finger CCHC domain-containing protein 17 |
| UniProt Gene Name: | ZCCHC17 |
| UniProt Entry Name: | NO40_HUMAN |
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