Human YWHAQ Recombinant Protein (RPPB2688)
- SKU:
- RPPB2688
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- YWHAQ
- Synonyms:
- 14-3-3 theta
- 14-3-3 tau
- 14-3-3 T-cell
- HS1
- Source:
- Escherichia Coli
- Uniprot:
- P27348
Description
Product Name: | Human YWHAQ Recombinant Protein |
Product Code: | RPPB2688 |
Size: | 20µg |
Species: | Human |
Target: | YWHAQ |
Synonyms: | 14-3-3 theta, 14-3-3 tau, 14-3-3 T-cell, HS1, YWHAQ, 1C5, 14-3-3 Tau, Tyr-3/Trp- 5 Monooxygenase Activation Protein Theta. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile filtered colorless solution. |
Formulation: | YWHAQ solution containing 20mM Tris 7.5. |
Stability: | YWHAQ Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
Purity: | Greater than 95.0% as determined by SDS-PAGE. |
Amino Acid Sequence: | MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWRVISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLKMKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYEILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN |
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed.
YWHAQ Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 245 amino acids (1-245) and having a molecular mass of 27 kDa. YWHAQ is purified by proprietary chromatographic techniques.
UniProt Protein Function: | 14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 2p25.1 Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex Molecular Function:protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding Biological Process: apoptosis; gene expression; negative regulation of transcription, DNA-dependent; programmed cell death; small GTPase mediated signal transduction; substantia nigra development; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008] |
UniProt Code: | P27348 |
NCBI GenInfo Identifier: | 112690 |
NCBI Gene ID: | 10971 |
NCBI Accession: | P27348.1 |
UniProt Secondary Accession: | P27348,Q567U5, Q5TZU8, Q9UP48, D6W4Z5, |
UniProt Related Accession: | P27348 |
Molecular Weight: | |
NCBI Full Name: | 14-3-3 protein theta |
NCBI Synonym Full Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
NCBI Official Symbol: | YWHAQ |
NCBI Official Synonym Symbols: | 1C5; HS1; 14-3-3 |
NCBI Protein Information: | 14-3-3 protein theta |
UniProt Protein Name: | 14-3-3 protein theta |
UniProt Synonym Protein Names: | 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1 |
Protein Family: | 14-3-3 protein |
UniProt Gene Name: | YWHAQ |
UniProt Entry Name: | 1433T_HUMAN |