Human XPNPEP1 Recombinant Protein (RPPB2419)
- SKU:
- RPPB2419
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- XPNPEP1
- Synonyms:
- X-Prolyl Aminopeptidase (Aminopeptidase P) 1
- Soluble
- XPNPEPL
- SAMP
- Source:
- Escherichia Coli
- Uniprot:
- Q9NQW7
Description
| Product Name: | Human XPNPEP1 Recombinant Protein |
| Product Code: | RPPB2419 |
| Size: | 20µg |
| Species: | Human |
| Target: | XPNPEP1 |
| Synonyms: | X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble,XPNPEPL, SAMP, X-Prolyl Aminopeptidase 1, Soluble, AminoacylprolineAminopeptidase, Cytosolic Aminopeptidase P, Soluble Aminopeptidase P, X-ProAminopeptidase 1, EC 3.4.11.9, XPNPEPL1, X-Prolyl Aminopeptidase(Aminopeptidase P)-Like, Aminopeptidase P, Cytosolic, Xaa-Pro Aminopeptidase 1,XPNPEP, APP1, Xaa-Pro aminopeptidase 1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | XPNPEP1 protein solution (1mg/ml) containing Phosphatebuffered saline (pH7.4) and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSEFELRRQ ASMPPKVTSE LLRQLRQAMR NSEYVTEPIQ AYIIPSGDAH QSEYIAPCDCRRAFVSGFDG SAGTAIITEE HAAMWTDGRY FLQAAKQMDS NWTLMKMGLK DTPTQEDWLV SVLPEGSRVGVDPLIIPTDY WKKMAKVLRS AGHHLIPVKE NLVDKIWTDR PERPCKPLLT LGLDYTGISW KDKVADLRLKMAERNVMWFV VTALDEIAWL FNLRGSDVEH NPVFFSYAII GLETIMLFID GDRIDAPSVK EHLLLDLGLEAEYRIQVHPY KSILSELKAL CADLSPREKV WVSDKASYAV SETIPKDHRC CMPYTPICIA KAVKNSAESEGMRRAHIKDA VALCELFNWL EKEVPKGGVT EISAADKAEE FRRQQADFVD LSFPTISSTG PNGAIIHYAPVPETNRTLSL DEVYLIDSGA QYKDGTTDVT RTMHFGTPTA YEKECFTYVL KGHIAVSAAV FPTGTKGHLLDSFARSALWD SGLDYLHGTG HGVGSFLNVH EGPCGISYKT FSDEPLEAGM IVTDEPGYYE DGAFGIRIENVVLVVPVKTK YNFNNRGSLT FEPLTLVPIQ TKMIDVDSLT DKECDWLNNY HLTCRDVIGK ELQKQGRQEALEWLIRETQP ISKQH |
X-Prolyl Aminopeptidase-1, also known as XPNPEP1 isa member of the peptidase M24B family. XPNPEP1 encodes the cytosolic form of ametalloaminopeptidase which catalyzes the cleavage of the N-terminal amino acidadjacent to a proline residue. Furthermore, XPNPEP1 plays a role in degradationas well as maturation of tachykinins, neuropeptides and peptide hormones.
XPNPEP1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 655 amino acids (1-623 a.a) andhaving a molecular mass of 73.4kDa.XPNPEP1 is fused to a 32 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | XPNPEP1: Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.4.11.9; Protease Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: cytoplasm Molecular Function:aminopeptidase activity; manganese ion binding; protein homodimerization activity Biological Process: proteolysis |
| NCBI Summary: | This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009] |
| UniProt Code: | Q9NQW7 |
| NCBI GenInfo Identifier: | 264681565 |
| NCBI Gene ID: | 7511 |
| NCBI Accession: | NP_001161076.1 |
| UniProt Related Accession: | Q9NQW7 |
| Molecular Weight: | |
| NCBI Full Name: | xaa-Pro aminopeptidase 1 isoform 2 |
| NCBI Synonym Full Names: | X-prolyl aminopeptidase 1 |
| NCBI Official Symbol: | XPNPEP1 |
| NCBI Official Synonym Symbols: | APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1 |
| NCBI Protein Information: | xaa-Pro aminopeptidase 1 |
| UniProt Protein Name: | Xaa-Pro aminopeptidase 1 |
| UniProt Synonym Protein Names: | Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; sAmp; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble |
| UniProt Gene Name: | XPNPEP1 |
| UniProt Entry Name: | XPP1_HUMAN |
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