Human Vitronectin/VTN Recombinant Protein (RPES2626)

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SKU:
RPES2626
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Vitronectin/VTN Recombinant Protein

Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM). Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM; Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site; plus cleavage sites for elastase; thrombin; and plasmin.

Product Name:Human Vitronectin/VTN Recombinant Protein (RPES2626)
Product Code:RPES2626
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Vitronectin, VN, S-Protein, Serum-Spreading Factor, V75, VTN
Accession:P04004
Sequence:Asp20-Leu478
Fusion tag:C-6His
Activity:Measured by the ability of the immobilized protein to support the adhesion of Jurkat cells.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Asp20-Leu478 is expressed with a 6His tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:53.4 kDa
AP Mol Mass:59 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 8.0.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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