Human TSSK6 Recombinant Protein (RPPB2673)
- SKU:
- RPPB2673
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- TSSK6
- Synonyms:
- TSSK6
- Testis-Specific Serine Kinase 6
- Cancer/Testis Antigen 72
- SSTK
- Source:
- Escherichia Coli
- Uniprot:
- Q9BXA6
Description
| Product Name: | Human TSSK6 Recombinant Protein |
| Product Code: | RPPB2673 |
| Size: | 20µg |
| Species: | Human |
| Target: | TSSK6 |
| Synonyms: | TSSK6, Testis-Specific Serine Kinase 6, Cancer/Testis Antigen 72, SSTK, Small Serine/Threonine Kinase, CT72, TSK-6, TSSK4, Serine/Threonine Protein Kinase SSTK, Testis-Specific Serine/Threonine-Protein Kinase 6, EC 2.7.11.1, TSSK-6, Serine/Threonine-Protein Kinase SSTK, Testis-Specific Kinase 6. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The TSSK6 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSGDKLL SELGYKLGRT IGEGSYSKVK VATSKKYKGT VAIKVVDRRR APPDFVNKFL PRELSILRGV RHPHIVHVFE FIEVCNGKLY IVMEAAATDL LQAVQRNGRI PGVQARDLFA QIAGAVRYLH DHHLVHRDLK CENVLLSPDE RRVKLTDFGF GRQAHGYPDL STTYCGSAAY ASPEVLLGIP YDPKKYDVWS MGVVLYVMVT GCMPFDDSDI AGLPRRQKRG VLYPEGLELS ERCKALIAEL LQFSPSARPS AGQVARNCWL RAGDSG |
Testis-specific serine/threonine-protein kinase 6 (TSSK6) is an intronless gene, which belongs to the CAMK Ser/Thr protein kinase family. The TSSK6 protein contains one protein kinase domain. TSSK6 is highly expressed in the testis and lowly expressed in the colon, prostate, thymus, small intestine, and peripheral blood leukocytes. TSSK6 interacts with the heatshock proteins HSPA8, HSPCB, and HAPA1A; these interactions seem to be essential for TSSK6 kinase activity. TSSK6 plays a role in DNA condensation during postmeiotic chromatin remodeling. In addition, TSSK6 is required for sperm production and function.
TSSK6 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 296 amino acids (1-273) and having a molecular mass of 32.7kDa.TSSK6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SSTK: a calmodulin-dependent kinase of the TSSK family. Protein type: Cancer Testis Antigen (CTA); Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; TSSK familyChromosomal Location of Human Ortholog: 19p13.11Cellular Component: cytoplasm; nucleusMolecular Function: ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activityBiological Process: protein amino acid phosphorylation; sperm chromatin condensation |
| UniProt Protein Details: | |
| NCBI Summary: | This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q9BXA6 |
| NCBI GenInfo Identifier: | 74761315 |
| NCBI Gene ID: | 83983 |
| NCBI Accession: | Q9BXA6.1 |
| UniProt Secondary Accession: | Q9BXA6,Q6ZMC4, Q96LJ4, B2R9F8 |
| UniProt Related Accession: | Q9BXA6 |
| Molecular Weight: | 30,331 Da |
| NCBI Full Name: | Testis-specific serine/threonine-protein kinase 6 |
| NCBI Synonym Full Names: | testis specific serine kinase 6 |
| NCBI Official Symbol: | TSSK6 |
| NCBI Official Synonym Symbols: | CT72; SSTK; TSSK4; FKSG82 |
| NCBI Protein Information: | testis-specific serine/threonine-protein kinase 6 |
| UniProt Protein Name: | Testis-specific serine/threonine-protein kinase 6 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 72; CT72; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase |
| Protein Family: | TSSK6-activating co-chaperone protein |
| UniProt Gene Name: | TSSK6 |
| UniProt Entry Name: | TSSK6_HUMAN |
Related Products
