Human TROVE2 Recombinant Protein (RPPB5019)
- SKU:
- RPPB5019
- Product type:
- Recombinant Protein
- Size:
- 50ug
- Species:
- Human
- Target:
- TROVE2
- Synonyms:
- 60 kDa SS-A/Ro ribonucleoprotein
- 60 kDa ribonucleoprotein Ro
- RoRNP
- 60 kDa Ro protein
- Source:
- Escherichia Coli
- Uniprot:
- P10155
Frequently bought together:
Description
| Product Name: | Human TROVE2 Recombinant Protein |
| Product Code: | RPPB5019 |
| Size: | 50µg |
| Species: | Human |
| Target: | TROVE2 |
| Synonyms: | 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa ribonucleoprotein Ro, RoRNP, 60 kDa Ro protein, Ro 60 kDa autoantigen, TROVE domain family member 2, Sjoegren syndrome type A antigen, SS-A, Sjoegren syndrome antigen A2, TROVE2, RO60, SSA2, RO-60. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The protein solution contains 6M Urea, 500mM NaCl, 500mM imidazole and 10mM Tris pH-6. |
| Stability: | RO-60 although stable at 4°C for 3 weeks, should be stored below -18°C. Please prevent freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
Ro 60 kDa autoantigen is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. SSA2 may stabilize these RNAs from degradation. Sera taken from patients with Systemic Lupus Erythematosus (SLE) often contains antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.
RO-60 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 60kDa. RO60 is fused to a 6 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. |
| UniProt Code: | P10155 |
| NCBI GenInfo Identifier: | 52788235 |
| NCBI Gene ID: | 6738 |
| NCBI Accession: | P10155.2 |
| UniProt Secondary Accession: | P10155,Q5LJ98, Q5LJ99, Q5LJA0, Q86WL3, Q86WL4, Q92787 Q9H1W6, B2RBB9, |
| UniProt Related Accession: | P10155 |
| Molecular Weight: | 23,299 Da |
| NCBI Full Name: | 60 kDa SS-A/Ro ribonucleoprotein |
| NCBI Synonym Full Names: | TROVE domain family member 2 |
| NCBI Official Symbol: | TROVE2 |
| NCBI Official Synonym Symbols: | RO60; SSA2; RORNP |
| NCBI Protein Information: | 60 kDa SS-A/Ro ribonucleoprotein |
| UniProt Protein Name: | 60 kDa SS-A/Ro ribonucleoprotein |
| UniProt Synonym Protein Names: | Ro 60 kDa autoantigen; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; SS-A; TROVE domain family member 2 |
| Protein Family: | 60 kDa SS-A/Ro ribonucleoprotein |
| UniProt Gene Name: | TROVE2 |
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