Human Troponin C/TNNC1 Recombinant Protein (RPES4392)
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- SKU:
- RPES4392
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human Troponin C/TNNC1 Recombinant Protein
Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
| Product Name: | Human Troponin C/TNNC1 Recombinant Protein (RPES4392) |
| Product Code: | RPES4392 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | CMD1Z,CMH13,TN-C,TNC,TNNC |
| Accession: | NP_003271.1 |
| Sequence: | Met 1-Glu161 |
| Fusion tag: | |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 18.4 kDa |
| AP Mol Mass: | 20 kDa |
| Formulation: | Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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