Human TPST1 Recombinant Protein (RPPB2344)
- SKU:
- RPPB2344
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- TPST1
- Synonyms:
- Tyrosylprotein Sulfotransferase 1
- EC 28220
- TPST-1
- Transport And Golgi Organization 13 Homolog A (Drosophila)
- Source:
- Escherichia Coli
- Uniprot:
- O60507
Description
| Product Name: | Human TPST1 Recombinant Protein |
| Product Code: | RPPB2344 |
| Size: | 20µg |
| Species: | Human |
| Target: | TPST1 |
| Synonyms: | Tyrosylprotein Sulfotransferase 1, EC 2.8.2.20, TPST-1, Transport And Golgi Organization 13 Homolog A (Drosophila), Transport And Golgi Organization 13 Homolog A, Protein-Tyrosine Sulfotransferase 1, Tyrosylprotein Sulfotransferase-1, TANGO13A, TPST1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | TPST1 protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH TGSMQHAMEC HHRIEERSQP VKLESTRTTV RTGLDLKANK TFAYHKDMPL IFIGGVPRSG TTLMRAMLDA HPDIRCGEET RVIPRILALK QMWSRSSKEK IRLDEAGVTD EVLDSAMQAF LLEIIVKHGE PAPYLCNKDP FALKSLTYLS RLFPNAKFLL MVRDGRASVH SMISRKVTIA GFDLNSYRDC LTKWNRAIET MYNQCMEVGY KKCMLVHYEQ LVLHPERWMR TLLKFLQIPW NHSVLHHEEM IGKAGGVSLS KVERSTDQVI KPVNVGALSK WVGKIPPDVL QDMAVIAPML AKLGYDPYAN PPNYGKPDPK IIENTRRVYK GEFQLPDFLK EKPQTEQVE |
TyrosylproteinSulfotransferase 1, also known as TPST1 is the enzyme whichcatalyzes the sulfation reaction of protein tyrosines, a post-translationalmodification of proteins. TPST1 belongs to the protein sulfotransferase family.In addition, TPST1 utilizes 3'-Phosphoadenosine-5'-phosphosulfate(PAPS) as the sulfonate donor and also binds proteins with target tyrosine residues to eventually form the tyrosine O-sulfate estergroup in addition to the desulfonated 3’-phosphoadenosine-5’-phosphate.
TPST1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 369 amino acids (26-370 a.a) and having a molecular mass of 42kDa.TPST1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | TPST1: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. Belongs to the protein sulfotransferase family. |
| UniProt Protein Details: | Protein type:EC 2.8.2.20; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 7q11.21 Cellular Component: Golgi apparatus; membrane Biological Process: inflammatory response |
| UniProt Code: | O60507 |
| NCBI GenInfo Identifier: | 4507665 |
| NCBI Gene ID: | 8460 |
| NCBI Accession: | NP_003587 |
| UniProt Secondary Accession: | O60507,Q6FGM7, A4D2M0, |
| UniProt Related Accession: | O60507 |
| Molecular Weight: | 42kDa (369aa) |
| NCBI Full Name: | protein-tyrosine sulfotransferase 1 |
| NCBI Synonym Full Names: | tyrosylprotein sulfotransferase 1 |
| NCBI Official Symbol: | TPST1 |
| NCBI Official Synonym Symbols: | TANGO13A |
| NCBI Protein Information: | protein-tyrosine sulfotransferase 1 |
| UniProt Protein Name: | Protein-tyrosine sulfotransferase 1 |
| UniProt Synonym Protein Names: | Tyrosylprotein sulfotransferase 1; TPST-1 |
| Protein Family: | Protein-tyrosine sulfotransferase |
| UniProt Gene Name: | TPST1 |
| UniProt Entry Name: | TPST1_HUMAN |
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