Human TPPP3 Recombinant Protein (RPPB4994)

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SKU:
RPPB4994
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
TPPP3
Synonyms:
Tubulin Polymerization-Promoting Protein Family Member 3
Synonyms:
Brain Specific Protein
Synonyms:
p25gamma
Synonyms:
TPPP/p20
Source:
Escherichia Coli
Uniprot:
Q9BW30
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Description

Product Name:Human TPPP3 Recombinant Protein
Product Code:RPPB4994
Size:20µg
Species:Human
Target:TPPP3
Synonyms:Tubulin Polymerization-Promoting Protein Family Member 3, Brain Specific Protein, p25gamma, TPPP/p20, p20.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The TPPP3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAASTDM AGLEESFRKF AIHGDPKASG QEMNGKNWAK LCKDCKVADG KSVTGTDVDI VFSKVKGKSA RVINYEEFKK ALEELATKRF KGKSKEEAFD AICQLVAGKE PANVGVTKAK TGGAVDRLTD TSRYTGSHKE RFDESGKGKG IAGRQDILDD SGYVSAYKNA GTYDAKVKK 

TPPP3 is a member of the TPPP family and is found in the cytoplasm. TPPP3 binds tubulin, has microtubule bundling activity takes part in mitosis and cell proliferation.

TPPP3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 199 amino acids (1-176) and having a molecular mass of 21.4kDa.TPPP3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:CGI-38: Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis. Belongs to the TPPP family.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: microtubule; cytoplasm

Molecular Function:tubulin binding

Biological Process: microtubule bundle formation

UniProt Code:Q9BW30
NCBI GenInfo Identifier:28380040
NCBI Gene ID:51673
NCBI Accession:Q9BW30.1
UniProt Secondary Accession:Q9BW30,Q49AH9, Q9Y326, Q9Y6H0,
UniProt Related Accession:Q9BW30
Molecular Weight:176
NCBI Full Name:Tubulin polymerization-promoting protein family member 3
NCBI Synonym Full Names:tubulin polymerization-promoting protein family member 3
NCBI Official Symbol:TPPP3  
NCBI Official Synonym Symbols:p20; CGI-38; TPPP/p20; p25gamma  
NCBI Protein Information:tubulin polymerization-promoting protein family member 3; brain specific protein
UniProt Protein Name:Tubulin polymerization-promoting protein family member 3
UniProt Synonym Protein Names:TPPP/p20
Protein Family:Tubulin polymerization-promoting protein family
UniProt Gene Name:TPPP3  
UniProt Entry Name:TPPP3_HUMAN
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