Human TP53AIP1 Recombinant Protein (RPPB4986)

(No reviews yet) Write a Review

제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.

주문
SKU:
RPPB4986
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
TP53AIP1
Synonyms:
p53-regulated apoptosis-inducing protein 1
Synonyms:
Tumor ProteinP53 Regulated Apoptosis Inducing Protein 1
Synonyms:
TP53AIP1
Synonyms:
p53AIP1
Source:
Escherichia Coli
Uniprot:
Q9HCN2
€0.00
Frequently bought together:

Description

Product Name:Human TP53AIP1 Recombinant Protein
Product Code:RPPB4986
Size:20µg
Species:Human
Target:TP53AIP1
Synonyms:p53-regulated apoptosis-inducing protein 1, Tumor ProteinP53 Regulated Apoptosis Inducing Protein 1, TP53AIP1, p53AIP1, P53-regulatedapoptosis-inducing protein 1 isoform a, TPIP1, P53AIP1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The TP53AIP1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHHSSGLVPRGSHMGSSSEASFR SAQASCSGAR RQGLGRGDQN LSVMPPNGRA QTHTPGWVSD PLVLGAQVHG GCRGIEALSV SSGSWSSATVWILTGLGLGL SRPFLPGATV LRDRPLGSAF ELSYDQKKAP LRLQ

Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 (TP53AIP1) is expressed mainly in the thymus, and is localized to the mitochondrion. p53 induces TP53AIP1 production which then mediates p53- dependent apoptosis. Alternatively spliced transcript variants encoding diverse isoforms are known for TP53AIP1.

TP53AIP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (1-124) and having a molecular mass of 15kDa.TP53AIP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:p53AIP1: May play an important role in mediating p53/TP53- dependent apoptosis. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Mitochondrial; Apoptosis

Chromosomal Location of Human Ortholog: 11q24

Cellular Component: mitochondrion

Biological Process: apoptosis

NCBI Summary:This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:Q9HCN2
NCBI GenInfo Identifier:74718882
NCBI Gene ID:63970
NCBI Accession:Q9HCN2.1
UniProt Secondary Accession:Q9HCN2,Q6NT40, Q7Z6F7, Q9HCN0, Q9HCN1,
UniProt Related Accession:Q9HCN2
Molecular Weight:124
NCBI Full Name:p53-regulated apoptosis-inducing protein 1
NCBI Synonym Full Names:tumor protein p53 regulated apoptosis inducing protein 1
NCBI Official Symbol:TP53AIP1  
NCBI Official Synonym Symbols:P53AIP1  
NCBI Protein Information:p53-regulated apoptosis-inducing protein 1
UniProt Protein Name:p53-regulated apoptosis-inducing protein 1
Protein Family:p53-regulated apoptosis-inducing protein
UniProt Gene Name:TP53AIP1  
UniProt Entry Name:TPIP1_HUMAN
View AllClose

Related Products