Human THOP1 Recombinant Protein (RPES0647)
- SKU:
- RPES0647
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human THOP1 Recombinant Protein
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
| Product Name: | Human THOP1 Recombinant Protein (RPES0647) |
| Product Code: | RPES0647 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1 |
| Accession: | P52888 |
| Sequence: | Lys2-Cys689 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 80.0 kDa |
| AP Mol Mass: | 85 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB, 100mM NaCl, 10% Glycerol, pH 7.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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